R. Mark Ghobrial, MD, PhD, FRCS (Ed)
New Director of Liver Transplant Program
The Methodist Hospital, Houston, TX
Dr. Ghobrial is currently Professor of Surgery in the Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at University of California, Los Angeles (UCLA). He is the Director of the Living Donor Liver Transplant Program and the Pancreas Transplantation Program at UCLA.
Dr. Ghobrial has been recruited to the Methodist Hospital, Houston, Texas as Director of the Comprehensive Liver Center; Director of Liver Transplantation ; Director of the Immunobiology Research Center and Professor of Surgery, Weill Cornell University School of Medicine, he will begin his position, March 1, 2008
After earning his MD degree from Cairo University Medical School in Egypt, he completed his internship at the Massachusetts General Hospital in Boston and his surgical residency at the University of Texas/M. D. Anderson Cancer Center in Houston. His clinical fellowship in multi-organ transplantation was conducted at the Dumont-UCLA Liver Transplant Center. During his surgical training, Dr. Ghobrial completed two postdoctoral basic science research fellowships in immunology at Harvard University and the University of Texas Medical School at Houston. He went on to receive his PhD in immunology from the Graduate School of Biomedical Sciences at the University of Texas.
As a researcher, Dr. Ghobrial maintains an active laboratory for basic science studies which focus on transplant immunomodulation and the inhibition of chronic rejection by indirect presentation of class I major histocompatibility (MHC) molecules and co-stimulatory pathways in allograft recipients. His clinical research interests include partial liver grafting, adult-to-adult living donor liver transplantation, immunosuppression and transplantation for hepatitis C. He is the principal or co-investigator of NIH-sponsored basic and clinical research studies, as well as multiple clinical trials associated with liver transplantation. Dr. Ghobrial is the author or co-author on well over 100 journal articles and book chapters. He lectures extensively on a variety of topics related to liver transplantation in both national and international forums, and has received multiple honors and awards. Currently, he is an active member of multiple transplantation and surgical societies, additionally, the American Surgical Association and is a fellow of the Royal College of Surgeon of Edingburgh.